Director Shareholding

GlaxoSmithKline PLC
4 February 2002

                              Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

1 February 2002    The Administrators of the SmithKline Beecham Employee Benefit 
                   Trust ('the Trust') notified the Company on the 4 February 
                   2002, that 72,109 Ordinary shares had been transferred from 
                   the Trust to participants of the SmithKline Beecham 1991 
                   Share Option Plan.

The Trust is a discretionary fund of which all employees or former employees of
SmithKline Beecham plc and its subsidiaries are potential beneficiaries. One of
the Company's directors, Dr J P Garnier is therefore, interested in the shares
held in the fund from time to time in the same way as other employees or former
employees of SmithKline Beecham plc and its subsidiaries.

S M Bicknell
Company Secretary

4 February 2002


                      This information is provided by RNS
            The company news service from the London Stock Exchange