Director Shareholding

GlaxoSmithKline PLC
30 October 2001

                             Directors' Interests


I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

29 October 2001    Abacus (GW) Trustees Limited, as trustee of The Glaxo        
                   Wellcome Employee Trust ('the Trust'), transferred 2,503     
                   Ordinary Shares in the Company to participants of the Glaxo 
                   Wellcome UK Share Option Scheme and the Glaxo Wellcome 
                   International Share Option Scheme.

The Company was advised of this transaction on 30 October 2001.

The Trust is a discretionary trust of which all employees or former employees
of GlaxoSmithKline Services plc (formerly Glaxo Wellcome plc) and its
subsidiaries are potential beneficiaries. Two of the Company's directors, Sir
Richard Sykes and John Coombe are therefore interested in the shares held in
the Trust from time to time in the same way as other employees or former
employees of GlaxoSmithKline Services plc and its subsidiaries.


S M Bicknell

Company Secretary


30 October 2001