Director Shareholding

GlaxoSmithKline PLC
2 January 2002

                             Directors' Interests

I give below details of changes in the directors' interests in the Ordinary
Shares and ADS Shares of GlaxoSmithKline plc.

On 31 December 2001, the following non-executive Directors were provisionally
allocated the following awards over Ordinary Shares and American Depository
Shares (ADSs) in the Company through the Annual Re-investment of Dividends
paid throughout 2001, as listed below.

SmithKline Beckman Non-Executive Directors Deferred Retainer Award - Annual
Dividend Reinvestment

Non-Executive Director    No. of ADR Shares    Average Price ($)

Mr D McHenry              416.772              49.727

SmithKline Beecham Non-Executive Directors Retainer Fee and Share Allocation
Award - Annual Dividend Reinvestment

Non-Executive     No. of Ordinary   Average Price No. of ADR    Average Price
Director          Shares            (£)           Shares        ($)

Sir Peter Walters 169.100           17.176

Mr P Allaire                                      9.603         49.726

Sir Christopher   18.339            17.176
Hogg

Mr D McHenry                                      9.603         49.726

Sir Ian Prosser   18.339            17.176

Dr Lucy Shapiro   28.627            17.176        9.603         49.726

Mr P Young        103.986           17.176        9.603         49.726



GlaxoSmithKline Non-Executive Directors Automatic Share Award and Elected
Share Award - Annual Dividend Reinvestment

Non-Executive     No. of Ordinary   Average Price No. of ADR    Average Price
Director          Shares            (£)           Shares        ($)

Sir Richard Sykes 23.578            17.176

Sir Roger Hurn    14.424            17.176

Sir Peter Walters 14.424            17.176

Mr P Allaire                                      1.930         49.726

Dr Michele        3.929             17.176
Barzach

Sir Christopher   3.929             17.176
Hogg

Sir Peter Job     6.894             17.176

Mr J McArthur                                     2.753         49.726

Mr D McHenry                                      1.930         49.726

Sir Ian Prosser   5.412             17.176

Dr Ronaldo        5.292             17.176
Schmitz

Dr Lucy Shapiro                                   1.930         49.726

Mr P Young                                        3.942         49.726



The Company was notified of this information on 2nd January 2002.

S M Bicknell

Company Secretary


2nd January 2002