Director Shareholding

GlaxoSmithKline PLC
2 May 2002

                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

30 April 2002    Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome 
                 Employee Trust ("the Trust"), transferred 1,711 Ordinary Shares
                 in the Company to participants of the Glaxo Wellcome 1999 Share 
                 Option Plan and the Glaxo Wellcome UK Share Option Scheme.


The Company was advised of these transactions on 1 May 2002.


The Trust is a discretionary trust of which all employees or former employees of
GlaxoSmithKline Services Unlimited (formerly Glaxo Wellcome plc) and its
subsidiaries are potential beneficiaries. Two of the Company's directors, Sir
Richard Sykes and John Coombe are therefore interested in the shares held in the
Trust from time to time in the same way as other employees or former employees
of GlaxoSmithKline Services Unlimited and its subsidiaries.




S M Bicknell
Company Secretary




2 May 2002




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