Director Shareholding

GlaxoSmithKline PLC
3 April 2002



                              Directors' Interests




I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned directors:

Sir Richard Sykes              Beneficial interest in 12 Ordinary Shares purchased under a Personal Equity Plan
                               on 2 April 2002 at £16.50.


                               Lady Janet Sykes (wife); beneficial interest in 7 Ordinary Shares purchased
                               under a Personal Equity Plan on 2 April 2002 at £16.50.

Mr J D Coombe                  Beneficial interest in 6 Ordinary Shares purchased under a Personal Equity Plan
                               on 2 April 2002 at £16.50.


                               Mrs G A Coombe (wife); beneficial interest in 4 Ordinary Shares purchased under
                               a Personal Equity Plan on 2 April 2002 at £16.50.

Sir Christopher Hogg           Beneficial interest in 19 Ordinary Shares purchased under a Personal Equity Plan
                               on 2 April 2002 at £16.50.

Sir Peter Job                  Beneficial interest in 2 Ordinary Shares purchased under a Personal Equity Plan
                               on 2 April 2002 at £16.50.



The Directors and the Company were advised of these transactions on 3rd April
2002.


S M Bicknell

Company Secretary


3rd April 2002



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