Director Shareholding

GlaxoSmithKline PLC
3 April 2002


                              Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

2 April 2002                  Abacus (GW) Trustees Limited, as trustee of The 
                              Glaxo Wellcome Employee Trust ("the Trust"), 
                              transferred 147,302 Ordinary Shares in the Company 
                              to participants of the Glaxo Wellcome 1999 Share 
                              Option Plan, the Glaxo Wellcome 1999 Long-Term
                              Incentive Plan and the Glaxo Wellcome 
                              International Share Option Scheme. The Trust
                              also sold 3,479 Ordinary Shares in the Company at 
                              £16.58 per share.


The Company was advised of this transaction on 3 April 2002.


The Trust is a discretionary trust of which all employees or former employees of
GlaxoSmithKline Services Unlimited (formerly Glaxo Wellcome plc) and its
subsidiaries are potential beneficiaries. Two of the Company's directors, Sir
Richard Sykes and John Coombe are therefore interested in the shares held in the
Trust from time to time in the same way as other employees or former employees
of GlaxoSmithKline Services Unlimited and its subsidiaries.




S M Bicknell
Company Secretary

3 April 2002


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