Director Shareholding

GlaxoSmithKline PLC
28 May 2002

                              Directors' Interests


I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.


27 May 2002   Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome 
              Employee Trust ("the Trust"), transferred 5,490 Ordinary Shares in 
              the Company to participants of the Glaxo Wellcome 1999 Long Term 
              Incentive Plan. The Trust also sold 3,674 Ordinary Shares in the 
              Company at £14.53 per share.


The Company was advised of these transactions on 28 May 2002.


The Trust is a discretionary trust of which all employees or former employees of
GlaxoSmithKline Services Unlimited (formerly Glaxo Wellcome plc) and its
subsidiaries are potential beneficiaries. One of the Company's directors, John
Coombe is therefore interested in the shares held in the Trust from time to time
in the same way as other employees or former employees of GlaxoSmithKline
Services Unlimited and its subsidiaries.


S M Bicknell

Company Secretary

28 May 2002




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