Director Shareholding

GlaxoSmithKline PLC
25 March 2002



                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.



21 March 2002    The Administrators of the GlaxoSmithKline US Retirement Savings 
                 Plan ("the Plan") notified GlaxoSmithKline plc on the 22 March 
                 2002, that as a result of movement in the fund on the 21 March 
                 2002, the number of Ordinary Share ADRs held by the fund had 
                 decreased from 18,695,306 to 18,620,968 at an average price
                 of $47.3500.


The Plan is a discretionary fund of which all employees or former employees of
SmithKline Beecham plc and its subsidiaries are potential beneficiaries. One of
the Company's directors, Dr J P Garnier is therefore, interested in the shares
held in the fund from time to time in the same way as other employees or former
employees of SmithKline Beecham plc and its subsidiaries.



S M Bicknell

Company Secretary


25 March 2002



                      This information is provided by RNS
            The company news service from the London Stock Exchange