Director Shareholding

GlaxoSmithKline PLC
26 March 2002



                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

25 March 2002                 Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome Employee Trust
                              ("the Trust"), transferred 3,400 Ordinary Shares in the Company to participants of
                              the Glaxo Wellcome International Share Option Scheme. The Trust also sold 39,024
                              Ordinary Shares in the Company at £16.555 per share, 7,984 Ordinary Shares in the
                              Company at £16.542 per share, 1,126 Ordinary Shares in the Company at £16.535 per
                              share, and 1,205 Ordinary Shares in the Company at £16.715 per share.




The Company was advised of these transactions on 26 March 2002.




The Trust is a discretionary trust of which all employees or former employees of
GlaxoSmithKline Services plc (formerly Glaxo Wellcome plc) and its subsidiaries
are potential beneficiaries. Two of the Company's directors, Sir Richard Sykes
and John Coombe are therefore interested in the shares held in the Trust from
time to time in the same way as other employees or former employees of
GlaxoSmithKline Services plc and its subsidiaries.






S M Bicknell

Company Secretary




26 March 2002




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