Director Shareholding

GlaxoSmithKline PLC
19 March 2002



                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.



15 March 2002                     The Administrators of the GlaxoSmithKline US Retirement Savings Plan ("the
                                  Plan") notified GlaxoSmithKline plc on the 18 March 2002, that as a result of
                                  movement in the fund on the 15 March 2002, the number of Ordinary Share ADRs
                                  held by the fund had increaased from 18,483,134 to 18,695,306 at an average
                                  price of $47.6200.


The Plan is a discretionary fund of which all employees or former employees of
SmithKline Beecham plc and its subsidiaries are potential beneficiaries. One of
the Company's directors, Dr J P Garnier is therefore, interested in the shares
held in the fund from time to time in the same way as other employees or former
employees of SmithKline Beecham plc and its subsidiaries.






S M Bicknell

Company Secretary


19 March 2002



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