Director Shareholding

GlaxoSmithKline PLC
3 May 2002

                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.


2 May 2002    Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome 
              Employee Trust ("the Trust"), transferred 12,400 Ordinary Shares 
              in the Company to a participant of the Glaxo Wellcome 
              International Share Option Scheme


The Company was advised of these transactions on 3 May 2002.



The Trust is a discretionary trust of which all employees or former employees of
GlaxoSmithKline Services Unlimited (formerly Glaxo Wellcome plc) and its
subsidiaries are potential beneficiaries. Two of the Company's directors, Sir
Richard Sykes and John Coombe are therefore interested in the shares held in the
Trust from time to time in the same way as other employees or former employees
of GlaxoSmithKline Services Unlimited and its subsidiaries.



S M Bicknell

Company Secretary

3 May 2002



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