Director Shareholding

GlaxoSmithKline PLC
16 July 2002



                              Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.



9 July 2002                The Administrators of SmithKline Beecham Employee Benefit Trust ("the Trust")
                           notified the Company on 15 July 2002 that the Trust purchased 2,120 Ordinary
                           shares for participants in the GlaxoSmithKline Annual Investment Plan at a price
                           of £13.2247.

10 July 2002               The Administrators of SmithKline Beecham Employee Benefit Trust ("the Trust")
                           notified the Company on 15 July 2002 that the Trust purchased 1,362 Ordinary
                           shares for participants in the SmithKline Beecham Bonus Investment Plan at a
                           price of £13.1372.

12 July 2002               The Administrators of the SmithKline Beecham Employee Benefit Trust ("the
                           Trust") notified the Company on the 15 July 2002 that 11,086 Ordinary shares had
                           been transferred from the Trust to participants of the SmithKline Beecham 1991
                           Share Option Plan.


The Trust is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and John Coombe are therefore interested in
the shares held in the fund from time to time in the same way as other employees
or former employees of GlaxoSmithKline plc and its subsidiaries.



S M Bicknell

Company Secretary


16 July 2002



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