Director Shareholding

GlaxoSmithKline PLC
23 September 2002

                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

19 September 2002             Abacus (GW) Trustees Limited, as trustee of The Glaxo Wellcome Employee Trust
                              ("the Trust"), transferred 1,934 Ordinary Shares in the Company to a participant
                              of the Glaxo Wellcome 1999 Long Term Incentive Plan. The Trust also sold 1,295
                              Ordinary Shares in the Company at £11.64 per share.




The Company was advised of this transaction on 20 September 2002.

The Trust is a discretionary trust of which all employees or former employees of
GlaxoSmithKline Services Unlimited (formerly Glaxo Wellcome plc) and its
subsidiaries are potential beneficiaries. One of the Company's directors, John
Coombe is therefore interested in the shares held in the Trust from time to time
in the same way as other employees or former employees of GlaxoSmithKline
Services Unlimited and its subsidiaries.


S M Bicknell
Company Secretary

23 September 2002


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