Director Shareholding

GlaxoSmithKline PLC
08 October 2002

                              Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

3 October 2002     The Administrators of the SmithKline Beecham Employee Benefit 
                   Trust ("the Trust") notified the Company on the 7 October 
                   2002 that 1,349 Ordinary shares had been purchased for 
                   participants in the SmithKline Beecham Bonus Investment
                   Plan at a price of £13.31 per share on 3 October 2002 and 523 
                   of these shares had been subsequently transferred to a plan 
                   participant.

                   The Trust also purchased 2,090 Ordinary shares for 
                   participants in the GlaxoSmithKline Annual Investment Plan 
                   on 3 October at a price of £13.31.


The Trust is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and John Coombe are therefore interested in
the shares held in the fund from time to time in the same way as other employees
or former employees of GlaxoSmithKline plc and its subsidiaries.



S M Bicknell

Company Secretary

8 October 2002



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