Director Shareholding

GlaxoSmithKline PLC
28 October 2002

                              Directors' Interests



I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

25 October 2002                   The Administrators of the GlaxoSmithKline US Retirement Savings Plan ("the
                                  Plan") notified GlaxoSmithKline plc on the 27 October 2002, that as a result of
                                  movement in the fund on the 25 October 2002, the number of Ordinary Share ADRs
                                  held by the fund had increased from 18,021,255 to 18,074,815 at an average price
                                  of $38.77.




The Trust is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and Mr J D Coombe are therefore interested
in the shares held in the fund from time to time in the same way as other
employees or former employees of GlaxoSmithKline plc and its subsidiaries.








S M Bicknell

Company Secretary


28 October 2002


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