Director Shareholding

GlaxoSmithKline PLC
06 January 2003

                              Directors' Interests


I give below details of a change in the interests in Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned Director arising from the
purchase of Ordinary Shares at a price of £11.94 per Ordinary Share on 3 January
2003 through the Company's ShareReward Plan ("the Plan") which Mr Coombe entered
on 5 October 2001:


Mr J D Coombe           Acquisition of 2 Ordinary Shares under the Dividend 
                        Reinvestment element of the Plan (Company contribution)


Mr Coombe and the Company were advised of this information on 6 January 2003.


S M Bicknell

Company Secretary

6 January 2003


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