Director Shareholding

GlaxoSmithKline PLC
10 January 2003


                              Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

9 January 2003                   The Administrators of the GlaxoSmithKline US 
                                 Retirement Savings Plan ("the Plan") notified 
                                 GlaxoSmithKline plc on 10 January 2003, that as 
                                 a result of movement in the fund on the 
                                 9 January 2003, the number of Ordinary Share 
                                 ADRs held by the fund had decreased from 
                                 18,320,180 to 18,281,390 at an average price of
                                 $39.73.

The Plan is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and Mr J D Coombe are therefore interested
in the shares held in the fund from time to time in the same way as other
employees or former employees of GlaxoSmithKline plc and its subsidiaries.

S M Bicknell

Company Secretary


10 January 2003


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