Director Shareholding

GlaxoSmithKline PLC
13 March 2003



                              Directors' Interests



I give below details of a change in the interests in Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned Director arising from the
purchase of Ordinary Shares at a price of £10.426 per Ordinary Share on 11 March
2003 through the Company's ShareReward Plan ('the Plan') which Mr Coombe entered
on 5 October 2001:



Mr J D Coombe                      Acquisition of 11 Ordinary Shares under the partnership element of the
                                   Plan (personal contribution)

                                   Acquisition of 11 Ordinary Shares under the matching element of the Plan
                                   (Company contribution)



Mr Coombe and the Company were advised of this information on 13 March 2003.






S M Bicknell

Company Secretary


13 March 2003


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