Director Shareholding

GlaxoSmithKline PLC
24 March 2003

                              Directors' Interests

I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

21 March 2003        The Administrators of the SmithKline Beecham Employee
                     Benefit Trust ('the Trust') notified the Company on 24
                     March 2003 that 11,023 Ordinary shares had been transferred
                     from the Trust to participants of the SmithKline Beecham
                     1991 Share Option Plan.


                     The Administrators of the SmithKline Beecham Employee
                     Benefit Trust, ('the Trust') notified the Company on 24
                     March 2003 that 485 Ordinary shares had been transferred
                     from the Trust to a participant in the UK Bonus Investment
                     Plan.

The Trust is a discretionary fund of which all employees or former employees of
GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the
Company's directors, Dr J P Garnier and John Coombe are therefore interested in
the shares held in the fund from time to time in the same way as other employees
or former employees of GlaxoSmithKline plc and its subsidiaries.


S M Bicknell
Company Secretary
24 March 2003


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