Director Shareholding

GlaxoSmithKline PLC
20 May 2003


                              Directors' Interests


I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.


19 May 2003                Abacus (GSK) Trustees Limited, as trustee of the
                           GlaxoSmithKline Employee Trust, ("the GSK Trust"),
                           transferred 4,004 Ordinary Shares in the Company to
                           participants in the SmithKline Beecham Employee Share
                           Option Plan 1991.


The Company was advised of this transaction on 20 May 2003.

The GSK Trust is a discretionary trust of which all employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. Two of the Company's directors, Dr J-P Garnier and Mr J D Coombe
are therefore interested in the shares held in the GSK Trust from time to time
in the same way as other employees or former employees of GlaxoSmithKline plc
and its subsidiaries.

S M Bicknell

Company Secretary

20 May 2003


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