Director Shareholding

GlaxoSmithKline PLC
02 April 2004

                             Directors' Interests

I give below details of changes in the directors' interests in the Ordinary
Shares and American Depository Shares (ADSs) of GlaxoSmithKline plc.

On 31 March 2004, the following non-executive Directors were provisionally
allocated the following awards over Ordinary Shares and ADSs in the Company
under the automatic share allocation arrangements for non-executive Directors
for the period of service from 1 January to 31 March 2004, as listed below.

Non Executive Director                Ordinary Shares       American Depository
                                                                 Shares (ADS)
Sir Christopher Hogg                       1,500
Dr Michele Barzach                          250
Mr Lawrence Culp                                                      125
Mr Crispin Davis                            250
Sir Peter Job                               250
John McArthur                                                         125
Donald McHenry                                                        125
Sir Ian Prosser                             250
Dr Ronaldo Schmitz                          250
Dr Lucy Shapiro                                                       125
Sir Robert Wilson                           250

At the same time the following non-executive Directors were provisionally
allocated the following awards over Ordinary Shares and ADSs in the Company
under the share election element of the share allocation arrangements for
non-executive Directors for the period of service from 1 January to 31 March
2004, as listed below.

Non Executive Director                Ordinary Shares       American Depositary
                                                                    Shares

                                                                     (ADS)

Sir Christopher Hogg                     3,495.9602
Mr Lawrence Culp                                                   450.5256
Mr Crispin Davis                         1,048.7881
Sir Peter Job                            1,048.7881
Sir Ian Prosser                           524.3940
Dr Ronaldo Schmitz                        512.7408


The Company and the directors were informed of these allocations on 1 April
2004.


S M Bicknell

Company Secretary

2 April 2004


                      This information is provided by RNS
            The company news service from the London Stock Exchange