Director Shareholding

GlaxoSmithKline PLC
20 April 2004

                              Director's Interests


I give below details of changes in interests in the Ordinary Share ADRs of
GlaxoSmithKline plc (each ADR represents two Ordinary Shares) in respect of the
under-mentioned Directors arising from the reinvestment of the dividend paid to
Ordinary Share ADR holders on 15 April 2004 through the US Global BuyDirect Plan
administered by The Bank of New York:


Mr D F McHenry                      Beneficial interest in 0.4847 of an Ordinary 
                                    Share ADR purchased at a price of $42.75 per 
                                    ADR.

Mr J H McArthur                     Beneficial interest in 59.7490 Ordinary 
                                    Share ADRs purchased at a price of $42.75 
                                    per ADR.

The Directors and the Company were advised of this information on 20 April 2004.

S M Bicknell

Company Secretary

20 April 2004




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