Director Shareholding

GlaxoSmithKline PLC
17 March 2004


                              Director's Interests


I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the under-mentioned director:-

Dr L Shapiro             The Administrators of the GlaxoSmithKline Scientific 
                         Advisory Board Share Allocation Plan notified 
                         GlaxoSmithKline plc on 17 March 2004 that 323 American
                         Depository Shares (ADS) had been purchased for Dr 
                         Shapiro at a price of $40.020 on 16 March 2004 as per 
                         the share election arrangements for the Scientific
                         Advisory Board. Dr Shapiro was also notified of this 
                         change on 17 March 2004.


SM Bicknell

Company Secretary

17 March 2004




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