Director Shareholding

GlaxoSmithKline PLC 28 September 2004 Directors' Interests I give below details of changes in interests in the Ordinary Shares of GlaxoSmithKline plc in respect of the undermentioned directors: Sir Christopher Hogg acquired a beneficial interest in 32 Ordinary Shares purchased under a Personal Equity Plan on 27 September 2004 at £11.79. Mr J D Coombe acquired a beneficial interest in 10 Ordinary Shares purchased under a Personal Equity Plan on 27 September 2004 at £11.79. Mrs G A Coombe (wife of Mr J D Coombe) acquired a beneficial interest in 8 Ordinary Shares purchased under a Personal Equity Plan on 27 September 2004 at £11.79. Sir Peter Job acquired a beneficial interest in 1 Ordinary Share purchased under a Personal Equity Plan on 27 September 2004 at £11.79. The Directors and the Company were advised of these transactions on 28 September 2004. S M Bicknell Company Secretary 28 September 2004 This information is provided by RNS The company news service from the London Stock Exchange

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