Director Shareholding

GlaxoSmithKline PLC
27 January 2005


                              Director's Interests


I give below details of changes in interests in the Ordinary Share ADRs of
GlaxoSmithKline plc in respect of the under-mentioned director:-
                         
Dr J P Garnier           The Administrators of the SmithKline Beecham Mid-Term 
                         Incentive Plan notified the Company and Dr Garnier on 
                         27 January 2005 that he had increased his interest by 
                         1,282.316 Ordinary Share ADRs at a price of 46.460 per 
                         Ordinary Share ADR following the re-investment of the
                         dividend paid to shareholders on 06 January 2005.


S M Bicknell
Company Secretary

27 January 2005



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