Director Shareholding

GlaxoSmithKline PLC
11 April 2005


                              Directors' Interests


The Administrators of the GlaxoSmithKline Executive Supplemental Savings Plan
notified the Company and the under-mentioned Directors on 11 April 2005 of
changes in their interests in Ordinary Share ADRs arising from an increase in
their interests under the Annual Investment Plan feature following the
re-investment of the dividend paid to shareholders on 07 April 2005 at a price
of $46.00 per share:-

Dr J P Garnier                                                  363.851
Dr T Yamada                                                     234.119



S M Bicknell
Company Secretary

11 April 2005




                      This information is provided by RNS
            The company news service from the London Stock Exchange