Transaction in Own Shares

GlaxoSmithKline PLC
28 February 2005


                              GlaxoSmithKline PLC



GlaxoSmithKline plc (the "Company") announces that in accordance with the
authority granted by shareholders at the Company's Annual General Meeting on 17
May 2004 it purchased 750,000 of it's Ordinary shares of 25 pence each ("shares
") on 28 February 2005 at a price of 1249.98 pence per share.



The Company intends to hold these shares in Treasury.



Following the purchase of these shares, the Company holds 76,248,000 of it's
shares in Treasury and has 5,863,461,892 shares in issue (excluding Treasury
shares).



This announcement does not constitute, or form part of, an offer or any
solicitation of an offer to purchase or subscribe for securities in any
jurisdiction.



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