Portfolio Update

Intl. Biotechnology Trust PLC
02 March 2006


FOR IMMEDIATE RELEASE                                                 02-Mar-06




To : The London Stock Exchange




International Biotechnology Trust plc




The Board of International Biotechnology Trust plc announces that the top ten
investments as at Tuesday 28 February 2006  were as follows:




            NAME % of Gross Assets


            Top 10 Investments
            Micromet         7.71
            Progenics Pharmaceuticals        4.82
            AnorMED        4.56
            Aderis Pharmaceuticals 4.16
            Cambridge Antibody Technology          3.72
            Genosis            3.68
            OSI Pharmaceuticals    3.04
            Pozen   2.96
            Sunesis Pharmaceuticals            2.63
            Alexion Pharmaceuticals           2.58




By Order of the Board
Schroder Investment Management Limited
Secretaries



Enquiries :
International Biotechnology Trust plc               Terry Croft   020 7658 3953


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