Blocklisting Interim Review

Phytopharm PLC
18 September 2006



                        BLOCKLISTING SIX MONTHLY RETURN

   INFORMATION PROVIDED ON THIS FORM MUST BE TYPED OR PRINTED ELECTRONICALLY.


To:   The FSA

Date: 18 September 2006       


1. Name of applicant:              Phytopharm plc



2. Name of scheme                  The Phytopharm 1996 Unapproved Discretionary
                                   Share Option 


3. Period of return:       From:   17 March 2006   To:  16 September 2006


4. Balance under scheme 
   from previous return:           140,712 Ordinary Shares of 1 pence


5. The amount by which the block   Nil
   scheme has been increased, if 
   the scheme has been increased 
   since the date of the last 
   return: 



6. Number of securities issued/    Nil
   allotted under scheme during 
   period:                         


7. Balance under scheme not yet    140,712 Ordinary shares of 1 pence
   issued / allotted at end of 
   period


8. Number and class of securities  400,000 Ordinary Shares of 1 pence 
   originally listed and the date 
   of admission


9. Total number of securities in   51,180,893 Ordinary Shares of 1 pence 
   issue at the end of the period



Name of contact                    Zoe McGowan

Address of contact                 Corpus Christi House, 9 West Street,
                                   Godmanchester

Telephone number of contact        01480 437697



Signed by

Company secretary
for and on behalf of

Name of applicant                  Phytopharm plc


If you knowingly or recklessly give false or misleading information you may be
liable to prosecution.

                        

                      This information is provided by RNS
            The company news service from the London Stock Exchange
                RKAAR