Rule 8.3 - BioFocus PLC

Northern Venture Trust PLC
11 October 2005


                                                                        FORM 8.3


   DEALINGS BY PERSONS WHO OWN OR CONTROL 1% OR MORE OF ANY CLASS OF RELEVANT
                                    SECURITY
              (Rule 8.3 of The City Code on Takeovers and Mergers)

Name of purchaser/vendor *                 NORTHERN VENTURE TRUST PLC

Company dealt in                           BIOFOCUS PLC

Relevant security dealt in                 ORD GBP 0.25

If a connected EFM, name of offeree/
offeror with which connected

If a connected EFM, nature of connection #

Date of dealing                            7 OCTOBER 2005 (PLEASE SEE BELOW FOR 
                                           FURTHER DEALINGS IN THE OFFER PERIOD)

DEALINGS +

Amount bought         Price per unit (currency must be stated)

Amount sold           Price per unit (currency must be stated)
77,806                GBP 1.12

Resultant total amount and percentage of the same relevant security owned  
or controlled
NIL

IS A SUPPLEMENTAL FORM 8 (DERIVATIVE)/FORM 8 (OPTION) ATTACHED? NO

Date of disclosure                      11 OCTOBER 2005

Contact name                            CHRISTOPHER MELLOR

Telephone number                        0191 244 6012

* Specify the owner or controller in addition to the person dealing. The naming
of nominees or vehicle companies is insufficient. In the case of disclosure of
dealings by fund managers on behalf of discretionary clients, the clients need
not be named.
# See the definition of 'connected fund managers and principal traders' in the
Definitions Section of the Code.
+ If disclosing dealings/holdings in derivatives or options, please attach
Supplemental Form 8 (Derivative) or Supplemental Form 8 (Option), as
appropriate.

For details of the Code's dealing disclosure requirements, see Rule 8 and its
Notes which can be viewed on the Takeover Panel's website at
www.thetakeoverpanel.org.uk.

FURTHER DEALINGS IN THE OFFER PERIOD

Date           No of shares sold     Price per share GBP
30/09/2005     19,451                1.14
04/10/2005     38,903                1.13
05/10/2005     19,840                1.12




                      This information is provided by RNS
            The company news service from the London Stock Exchange