Blocklisting Interim Review

Oxford Biomedica PLC
18 May 2006


                    BLOCKLISTING SIX MONTHLY REVIEW


1. NAME OF COMPANY:

   OXFORD BIOMEDICA PLC


2. NAME OF SCHEME:

   SHARE OPTION SCHEME


3. PERIOD OF RETURN:     FROM:                   TO:

                         19 NOVEMBER 2005        18 MAY 2006


4. NUMBER AND CLASS OF SHARE(S)
   (AMOUNT OF STOCK/DEBT SECURITY)
   NOT ISSUED UNDER SCHEME:

   8,205,290 ORDINARY SHARES OF 1P EACH


5. NUMBER OF SHARES ISSUED/ALLOTTED
   UNDER SCHEME DURING PERIOD:

   1,164,119 ORDINARY SHARES OF 1P EACH



6. BALANCE UNDER SCHEME NOT YET ISSUED/ALLOTTED 
   AT END OF PERIOD:

   7,041,171 ORDINARY SHARES OF 1P EACH



7. NUMBER AND CLASS OF SHARE(S) 
   (AMOUNT OF STOCK/DEBT SECURITIES) 
   ORIGINALLY LISTED AND THE DATE OF ADMISSION:

   17,383,143 ORDINARY SHARES OF 1P EACH:  DATE ADMITTED 9 MAY 2001

PLEASE CONFIRM TOTAL NUMBER OF SHARES IN ISSUE AT THE END OF THE PERIOD
IN ORDER FOR US TO UPDATE OUR RECORDS.

   499,602,329 ORDINARY SHARES OF 1P EACH


CONTACT FOR QUERIES

NAME:                    ANDREW WOOD

TELEPHONE:               01865 783000

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