Notification of Shares

Oxford Biomedica PLC
01 February 2008


For immediate release                                            1 February 2008



                              Oxford BioMedica Plc



                   Notifications of Major Interests in Shares


TR-1: Notifications of Major Interests in Shares


1. Identity of the issuer or the underlying issuer of
existing shares to which voting rights are attached:
                                                            Oxford BioMedica Plc


2. Reason for notification (yes/no)
                                                                           Yes

An acquisition or disposal of voting rights


An acquisition or disposal of financial instruments which may result in the acquisition
of shares already issued to which voting rights are attached


An event changing the breakdown of voting rights


Other (please specify):______________


3. Full name of person(s) subject to notification    Legal & General Group Plc (L&G)
obligation:
                                                     Legal & General Assurance (Pensions Management)
                                                     Limited (PMC)
4. Full name of shareholder(s) (if different from
3):


5. Date of transaction (and date on which the        30 January 2008
threshold is crossed or reached if different):


6. Date on which issuer notified:                    31 January 2008


7. Threshold(s) that is/are crossed or reached:      3% to 4%


8: Notified Details
A: Voting rights attached to shares


Class/type of       Situation previous to the Resulting situation after the triggering transaction
shares              triggering transaction

If possible use
ISIN code
                    Number of    Number of    Number of    Number of voting rights Percentage of voting
                    shares       voting       shares                               rights
                                 rights





                                                           Direct       Indirect   Direct     Indirect
GB0006648157        16,729,883   16,729,883   22,476,084   22,476,084              4.18%




B: Financial Instruments


Resulting situation after the triggering transaction


Type of financial    Expiration date      Exercise/ conversion No. of voting rights  Percentage of voting
instrument                                period/date          that may be acquired  rights
                                                               (if the instrument
                                                               exercised/converted)





Total (A+B)


Number of voting rights                              Percentage of voting rights
22,476,084                                           4.18%


9. Chain of controlled undertakings through which the voting rights and /or the financial instruments are effectively
held, if applicable:
Legal & General Group Plc (Direct and Indirect) (Group)

Legal & General Investment Management (Holdings) Limited (LGIMH) (Direct and Indirect)

Legal & General Investment Management Limited (Indirect) (LGIM)




Proxy Voting:
10. Name of proxy holder:


11. Number of voting rights proxy holder will
cease to hold:


12. Date on which proxy holder will cease to hold
voting rights:


13. Additional information:


14 Contact name:                                   Andrew Wood


15. Contact telephone name:                        01865 783000


                   Registered Holder                                          Holding           %

Legal & General Group PLC (Direct and Indirect) (Group)                    22,476,084       4.18%
                   Legal & General Assurance Society Limited
                   Legal & General Pensions Limited
                   Legal & General Assurance (Pensions Management)
                   Limited

Legal & General Investment Management (Holdings) Limited (Direct)          20,153,912       3.75%
                   Legal & General Assurance (Pensions Management)
                   Limited

Legal & General Insurance Holdings Limited (Direct)                        20,153,912       3.75%
                   Legal & General Assurance (Pensions Management)
                   Limited

Legal & General Assurance (Pensions Management) Limited                    20,153,912       3.75%
                   Legal & General Assurance Society Limited
                   Legal & General Pensions Limited





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