QIAGEN Reports Strong First Quarter 2008 Results

Corporate news announcement processed and transmitted by Hugin ASA. The issuer is solely responsible for the content of this announcement. ---------------------------------------------------------------------- -------------- Corporate news announcement processed and transmitted by Hugin ASA. The issuer is solely responsible for the content of this announcement. ---------------------------------------------------------------------- -------------- * 62% Revenue Growth, 10% Organic Growth * 79% Adjusted Operating Income Growth * $0.18 Adjusted EPS Venlo, The Netherlands, May 5, 2008 - QIAGEN N.V. (Nasdaq: QGEN; Frankfurt, Prime Standard: QIA) today announced the results of operations for its first quarter ended on March 31, 2008.   The reported net sales as well as adjusted earnings per share for the first quarter 2008 exceeded the guidance provided by the Company on February 12, 2008.   QIAGEN's first quarter 2008 results include the results of operations of Digene Corporation and eGene, Inc. as well as certain charges related to these acquisitions which occurred after the first quarter of 2007.   First Quarter 2008 Results   The Company reported that consolidated net sales for its first quarter 2008 increased 62% to $207.1 million from $127.9 million for the same quarter in 2007. Reported operating income for the quarter increased 15% to $33.0 million from $28.8 million in the same quarter of 2007, and net income for the quarter increased 2% to $20.3 million from $19.9 million in the same quarter of 2007. Diluted earnings per share for the first quarter decreased to $0.10 in 2008 (based on 205.1 million weighted average shares and share equivalents outstanding) from $0.13 in 2007 (based on 156.2 million weighted average shares and share equivalents outstanding).   On an adjusted basis, first quarter operating income increased 79% to $58.7 million in 2008 from $32.8 million in 2007, and first quarter 2008 adjusted net income increased 63% to $36.9 million from $22.6 million in 2007. Adjusted diluted earnings per share increased to $0.18 in the first quarter 2008 from $0.14 in 2007.   QIAGEN's First Quarter 2008 (in US$ millions, except per share information)   Q1 2008 Q1 2007 Growth         Net sales 207.1 127.9 62% Operating income, adj.[1] 58.7 32.8 79% Net income, adj.[1] 36.9 22.6 63% EPS, adj.[1] (US$) 0.18 0.14 29%                 [1] excluding acquisition, integration and restructuring related charges as well as   amortization of acquired IP and equity-based compensation (SFAS 123R)   as detailed in the table below.   QIAGEN has regularly reported adjusted results to give additional insight into its financial performance. Adjusted results should be considered in addition to the reported results prepared in accordance with generally accepted accounting principles, but should not be considered a substitute. The Company believes certain items should be excluded from adjusted results when they are either outside of our ongoing core operations or vary significantly from period to period, which affects the comparability of results with the Company's competitors and its own prior periods. Costs and charges excluded from adjusted results include acquisition, integration, and restructuring related costs, acquisition-related amortization, and compensation cost due to equity based compensation in accordance with Statement of Financial Accounting Standards No. 123 (Revised) (SFAS 123R).   QIAGEN's Adjustments to Gross Profit, Operating   Income, Net Income and EPS In US$ millions unless indicated Q1 2008 Q1 2007       Gross profit reported 141.2 87.1 Amortization of acquired IP 10.9 1.9 SFAS 123R impact 0.2 0.0 Gross profit, adjusted 152.3 89.0       Operating income, reported 33.0 28.8 Acquisition and integration related 8.7 0.7 charges (incl. COS) Relocation and restructuring charges 0.5 0.4 Amortization of acquired IP (incl. 14.5 2.6 COS) SFAS 123R impact (incl. COS) 2.0 0.3 Operating income, adjusted 58.7 32.8       Net income, reported 20.3 19.9 Acquisition and integration related 5.6 0.5 charges Relocation and restructuring charges 0.3                0.3 Amortization of acquired IP 9.4 1.7 SFAS 123R impact 1.3 0.2 Net income, adjusted 36.9 22.6       Weighted average number of basic 195,993,000 150,389,000 common shares Weighted average number of diluted 205,126,000 156,199,000 common shares EPS, reported in US$ 0.10 0.13 EPS, adjusted in US$ 0.18 0.14           "QIAGEN experienced a successful start into 2008," said Peer Schatz, QIAGEN's Chief Executive Officer. "We saw strong revenue and net income growth and exciting momentum in our strategic position. We launched 19 new products in the area of sample and assay technologies and are managing a strong pipeline of new products. Most notably, our new flagship, the QIAsymphony platform, launched in January 2008, has received a very strong reception by our customers across all segments."   "Our financial statements also give evidence to significant value creation from our most recent acquisitions. The integrations of our recently acquired businesses are fully on track to meet their targets in terms of cost synergies, accretion and timelines. In January 2008, QIAGEN launched the QIAxcel system which is based on the capillary electrophoresis technology acquired in the transaction with eGene. QIAGEN also initiated marketing of QIAGENs new line of digene HC2 tests added in the Digene acquisition through merged laboratory sales channels. In addition, we significantly expanded our clinical sales channel, launched new tactical and marketing campaigns and created access for our products in countries not previously served directly."    "We are very pleased with our financial performance in this first quarter of 2008. Reported revenues and adjusted earnings per share came in very strong and exceeded our expectations. We experienced a strong adjusted operating margin jump to 28% in the first quarter 2008 which corresponds to a growth rate of 79% year over year reflective of the attained cost synergies following the acquisition of Digene," said Roland Sackers, QIAGEN's Chief Financial Officer.   "Revenue growth for the first quarter was 62% and was fueled by a strong organic growth of 10% and a positive contribution of 43% from acquisitions. Our consumable portfolio contributed 68% growth (59% at constant exchange rates). In the wake of new product introductions in QIAGEN's instrumentation business (such as the QIAsymphonySP and QIAxcel) which will mostly start shipping late in the second quarter, this product area recorded a growth rate at constant exchange rates of 3%. Net sales in North America for the first quarter 2008 represented approximately 50% of our overall business and recorded a growth rate of 106% while European sales, which represent approximately 38% of our revenues showed a growth rate of 21% at constant exchange rates. Despite the expiration of a number of third party distribution agreements end of 2007 which we had inherited through previous acquisitions, net sales in Asia remained strong, showing a growth rate of 14% at constant exchange rates."   QIAGEN's First Quarter 2008 at Constant       Currencies   2008 2008 2007 Growth Rates As percentage Q1 Q1 Q1     of net sales,   Constant     Constant unless indicated Reported Currency Reported Reported Currency             Consumables 92% 92% 89% 68% 59% Instruments 7% 7% 10% 11% 3% Others 1% 1% 1% 71% 59% Total revenues 100% 100% 100% 62% 53%             Gross margin 68% 69% 68% 62% 55% Gross margin, adj.[1] 74% 75% 70% 71% 64%             Operating income margin 16% 17% 23% 15% 15% Operating income margin, 28% 30% 26% 79% 78% adj. [1]             Net income margin 10% 10% 16% 2% -1% Net income margin, adj. 18% 18% 18% 63% 60% [1]             EPS in US$ per share 0.10 0.10 0.13 -23% -23% EPS in US$ per share, 0.18 0.18 0.14 29% 29% adj. [1]                         [1] excluding acquisition, integration and restructuring related charges as well as   amortization of acquired IP and equity-based compensation (SFAS 123R)   as detailed in the table above.   Detailed information on QIAGEN's business and financial performance will be presented in its conference call on May 6, 2008 at 9:30am ET. The corresponding presentation slides will be available for download on QIAGEN's website at www.qiagen.com/goto/050608. A webcast of the conference call will be available on the same website at www.qiagen.com/goto/050608.     QIAGEN - Sample and Assay Technologies Highlights:   * QIAGEN and BioHelix entered into a non-exclusive worldwide license and supply agreement for BioHelix's proprietary Helicase Dependent Amplification (HDA) technology. Unlike conventional amplification technologies such as polymerase chain reaction (PCR), which requires thermocycling, HDA works at a constant temperature, eliminating the need for complex and costly instrumentation. HDA is compatible with a large range of detection instruments including those incorporated in the QIAsymphony and the QIAensemble platforms. The technology can be the basis to a wide field of singleplex and/or multiplex assays for use in research, pharmaceutical development, applied markets or molecular diagnostics. * QIAGEN launched 19 new products in the area of sample & assay technologies including the QIAxcel for fully automated capillary electrophoresis to separate and analyze DNA, RNA and proteins, the QIAsymphonySP, the first system of a novel modular processing platform which can be integrated to automate entire workflows and the EZ1 Advanced, the next generation of our successful EZ1 for the fully automated low throughput sample preparation with prefilled cartridges, introduced in 2004. In addition QIAGEN launched a number of assay technologies including two tests for the applied testing markets to detect bovine virus diarrhea virus (BVD) in cattle and Taylorella equigenitalis in horses. * QIAGEN opened a new Service Solutions Center in Singapore for the Asia-Pacific region. The facility completes the Company's global Service Solution Network by adding a center in the Asia-Pacific region to its existing centers in the United States (Valencia, CA, and Germantown, MD), Europe (Hilden, Crawley, Paris) and Japan (Tokyo). * QIAGEN and the Center for Molecular Medicine (CMM) established a research collaboration for molecular diagnostic markers for breast cancer and other women's health issues. CMM's privileged access to clinical samples, its molecular analysis capabilities as well as XenoBase, a one-of-a-kind software and database system developed at the Van Andel Research Institute make it a perfect partner to identify clinically actionable associations between diseases, biomarkers and treatments. Based on the result of QIAGEN's initial research, CMM may also provide laboratory-based genomics and proteomics services to assist QIAGEN in the development and validation of new molecular diagnostic tests. About QIAGEN:   QIAGEN N.V., a Netherlands holding company, is the leading global provider of sample and assay technologies. Sample technologies are used to isolate and process DNA, RNA and proteins from biological samples such as blood or tissue. Assay technologies are used to make such isolated biomolecules visible. QIAGEN has developed and markets more than 500 consumable products as well as automated solutions for such consumables. The company provides its products to molecular diagnostics laboratories, academic researchers, pharmaceutical and biotechnology companies, and applied testing customers for purposes such as forensics, animal or food testing and pharmaceutical process control. QIAGEN's assay technologies include one of the broadest panels of molecular diagnostic tests available worldwide. This panel includes the only FDA-approved test for human papillomavirus (HPV), the primary cause of cervical cancer. QIAGEN employs more than 2,700 people in over 30 locations worldwide. Further information about QIAGEN can be found at www.qiagen.com.     Certain of the statements contained in this news release may be considered forward-looking statements within the meaning of Section 27A of the U.S. Securities Act of 1933, as amended, and Section 21E of the U.S. Securities Exchange Act of 1934, as amended. To the extent that any of the statements contained herein relating to QIAGEN's products, markets, strategy or operating results are forward-looking, such statements are based on current expectations that involve a number of uncertainties and risks. Such uncertainties and risks include, but are not limited to, risks associated with management of growth and international operations (including the effects of currency fluctuations and risks of dependency on logistics), variability of operating results, the commercial development of the applied testing markets, clinical research markets and proteomics markets, women's health/HPV testing markets, nucleic acid-based molecular diagnostics market, and genetic vaccination and gene therapy markets, changing relationships with customers, suppliers and strategic partners, competition, rapid or unexpected changes in technologies, fluctuations in demand for QIAGEN's products (including fluctuations due to the level and timing of customers' funding, budgets, and other factors), our ability to obtain regulatory approval of our infectious disease panels, difficulties in successfully adapting QIAGEN's products to integrated solutions and producing such products, the ability of QIAGEN to identify and develop new products and to differentiate its products from competitors' products, market acceptance of QIAGEN's new products and the integration of acquired technologies and businesses. For further information, refer to the discussions in reports that QIAGEN has filed with, or furnished to, the U.S. Securities and Exchange Commission (SEC).   ###     QIAGEN N.V. CONDENSED CONSOLIDATED STATEMENTS OF INCOME (unaudited)                   Three months (in thousands, except per share   data)   ended March 31,       2008   2007 Net sales    $            207,106    $            127,879                                   Cost of sales   55,056   38,926 Cost of sales - acquisition related intangible                                    amortization   10,826   1,907   Gross profit    141,224     87,046              Operating Expenses:         Research and                                     development   21,369   11,531 Sales and                                     marketing   54,078   31,303 General and                                     administrative   19,903   13,626 Acquisition, integration and                                          related costs   8,725   690 Acquisition related intangible                                     amortization        3,651   691 Relocation and restructuring                                             costs   460   409 Total operating expenses    108,186     58,250              Income from operations    33,038     28,796              Other Income (Expense):                             Interest income    2,972    5,166                    (Interest expense)   (10,451)   (4,691) Other income                    (expense), net    2,135       (254) Total other income (expense)   (5,344)    221              Income before provision for income taxes and   minority interest    27,694     29,017  Provision for   income taxes    7,301     9,150                         Minority interest    60    -      $                Net income    $              20,333   19,867                         Weighted average number of diluted   common shares    205,126,000     156,199,000              Diluted net income  $                 $                   per common share   0.10   0.13              Diluted net income per common share excluding acquisition, integration and restructuring related charges as well as amortization of acquired IP and equity-based compensation (SFAS $                 $                   123R)   0.18    0.14            QIAGEN N.V. CONDENSED CONSOLIDATED BALANCE SHEETS                                         (in   thousands)       March 31,   December 31,             2008   2007   Assets     (unaudited)                         Current Assets:             Cash and cash equivalents    $          351,561    $          347,320                                              Marketable securities   - 2,313                   5,609                     Notes receivable   5,139     Accounts receivable, net               152,459               136,707     Income taxes receivable                 11,343                 10,696     Inventories                 99,095                 88,346     Deferred income taxes                 38,532                 23,732     Prepaid expenses and other                 37,063                 33,693         Total current assets               695,662               647,946                     Long-Term Assets:             Property, plant and equipment, net               299,597               283,491     Goodwill             1,113,354             1,107,882     Intangible assets, net               631,078               639,107     Deferred income taxes                 75,092                 72,128     Other assets                 27,463                 24,620   Total long-term           2,146,584             2,127,228       assets                           Total assets    $       2,842,246    $       2,775,174                     Liabilities and Shareholders' Equity                             Current Liabilities:            $                     $                     Short term loans   -   4   Current portion of capital lease                 2,962        obligations                2,769     Accounts payable                 37,822                 40,379     Accrued and other liabilities                 99,595               104,220     Income taxes payable                 22,617                 13,456                   6,739                     Deferred income taxes   4,903   Total current             169,735               165,731       liabilities                       Long-Term Liabilities:           Long-term debt, net of current             950,000               950,000   portion     Capital lease obligations, net of               33,182                 33,017   current portion       Deferred income taxes               226,838               225,893                 10,832                     Other     8,405   Total long-term           1,220,852             1,217,315       liabilities                       Minority interest in consolidated                    411                      subsidiaries   553                     Shareholders' Equity:             Common shares, EUR .01 par value:           Authorized--410,000,000           shares     Issued and       outstanding--196,296,429     shares        in 2008 and                 2,190                   195,335,076 shares in 2,175     2007     Additional             937,243               925,597     paid-in-capital         Retained earnings               409,112               388,779   Accumulated other             102,703                 75,024     comprehensive income     Total shareholders'           1,451,248             1,391,575       equity                       Total liabilities and  $       2,842,246    $       2,775,174     shareholders' equity                         Contacts:   Roland Sackers Dr. Solveigh Mähler Chief Financial Officer Director Investor Relations QIAGEN N.V. QIAGEN N.V. e-mail: +49 2103 29 11710 roland.sackers@qiagen.com       e-mail: solveigh.maehler@qiagen.com     Albert F. Fleury Associate Director Investor Relations North America QIAGEN N.V. +1 301 944 7028 e-mail: albert.fleury@qiagen.com --- End of Message --- Qiagen N.V. Spoorstraat 50 KJ Venlo Netherlands WKN: 901626; ISIN: NL0000240000; Index: HDAX, MIDCAP, Prime All Share, TECH All Share, TecDAX; Listed: Prime Standard in Frankfurter Wertpapierbörse, Freiverkehr in Börse Berlin, Freiverkehr in Börse Düsseldorf, Freiverkehr in Hanseatische Wertpapierbörse zu Hamburg, Freiverkehr in Niedersächsische Börse zu Hannover, Freiverkehr in Bayerische Börse München, Freiverkehr in Börse Stuttgart;

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