Offer discussions terminated

Sareum Holdings PLC
25 April 2005

Sareum Holdings plc ("Sareum" or "the Company")

Termination of talks

On 4 March 2005, Sareum announced that it was in discussions with a party that
may or may not lead to an offer being made for the Company. The Company
announces that these discussions have terminated.

The Sareum directors continue to work to develop the Company's structure-based
drug discovery and services business and remain confident about its future
prospects.


                      This information is provided by RNS
            The company news service from the London Stock Exchange