Holding(s) in Company

Smiths Group PLC
10 November 2006


10 NOVEMBER 2006

NOTIFICATION OF MAJOR INTERESTS IN SHARES

LISTING RULE LR 9.6.7 R

1.       Name of listed company: SMITHS GROUP PLC

2.       Name of shareholder with a major interest:

(A)           FMR CORP. AND ITS DIRECT AND INDIRECT SUBSIDIARIES AND

(B)           FIDELITY INTERNATIONAL LIMITED AND ITS DIRECT AND INDIRECT
              SUBSIDIARIES

3.       Please state whether notification indicates that it is regarding the
holding of the shareholder named in 2 above; in respect of a non-beneficial
interest; or in the case of an individual holder if it is a holding of that
person's spouse or children under the age of 18:

NOTIFICATION ON BEHALF OF FMR CORP. AND ITS DIRECT AND INDIRECT SUBSIDIARIES AND
FIDELITY INTERNATIONAL LIMITED AND ITS DIRECT AND INDIRECT SUBSIDIARIES AND MR
EDWARD C JOHNSON 3D, A PRINCIPAL SHAREHOLDER OF FMR CORP. AND FIDELITY
INTERNATIONAL LIMITED, OF DISCLOSABLE INTERESTS ARISING UNDER S208(4)(b) OF THE
COMPANIES ACT 1985.

4.       Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them:

SHAREHOLDER                                                           SHARES

STATE STREET HONG KONG                                                18,500
STATE STREET BANK AND TR CO                                         315,800
BNP PARISBAS, PARIS                                                 296,000
BANK OF NEW YORK EUROPE LDN                                       3,198,800
TRUST & CUST SRVCS BK LTD, TOKO                                       20,260
NOMURA TRUST AND BANKING                                              37,700
MASTER TRUST BANK OF JAPAN                                          187,400
ING LUXEMBORUG                                                        20,300
NORTHERN TRUST LONDON                                                 42,900
STATE STREET BANK AUSTRALIA (C                                        98,400
STATE STR BK AND TR CO LNDN (S                                      120,920
NORTHERN TRUST LONDON                                               162,500
JP MORGAN, BOURNEMOUTH                                              193,900
BROWN BROS HARRIMAN LTD LUX                                       1,841,214
JP MORGAN, BOURNEMOUTH                                            4,540,916
BERMUDA TRUST FAR EAST HK                                           259,304
JP MORGAN, BOURNEMOUTH                                            7,824,783
MELLON BANK NA                                                        17,900
MELLON BANK NA                                                        35,700
NORTHERN TRUST LONDON                                                 83,700
NORTHERN TRUST CO                                                   102,200
STATE STREET BANK AND TR CO                                         667,500
BROWN BROS HARRIMAN AND CO                                          942,300
JPMORGAN CHASE BANK                                             16,363,757
ROYAL TRUST -TORONTO                                                  20,719
BROWN BROS HARRIMAN AND CO                                            37,700
CIBC MELLON TRUST                                                   115,480
BANK OF NEW YORK                                                    365,200
JPMORGAN CHASE                                                      556,800
MELLON BANK NA                                                      673,720
NORTHERN TRUST CO                                                   858,164
STATE STREET BANK AND TR CO                                       1,804,763
DEXIA PRIVATBANK                                                       9,500
SOCIETE GENERALE                                                      42,800
JPMORGAN CHASE BANK                                                   44,600
CHASE MANHTTN BK AG FRNKFRT (S                                        82,900
MIDLAND SECURITIES SERVICES                                         124,140
BANKERS TRUST LONDON                                                264,380
HSBC BANK PLC                                                       462,000
BANK OF NEW YORK BRUSSELS                                           773,369
MELLON BANK                                                         981,800
STATE STR BK AND TR CO LNDN (S                                    1,699,519
JP MORGAN, BOURNEMOUTH                                            2,144,780
NORTHERN TRUST LONDON                                             3,727,780
JPMORGAN CHASE BANK                                               3,290,658

5.       Number of shares / amount of stock acquired: NOT DISCLOSED

6.       Percentage of issued class*: N/A

7.       Number of shares / amount of stock disposed: NOT DISCLOSED

8.       Percentage of issued class*: N/A

9.       Class of security: ORDINARY SHARES OF 25p

10.     Date of transaction: NOT DISCLOSED

11.     Date listed company informed: 10 NOVEMBER 2006

12.     Total holding following this notification: 55,473,426 SHARES

13.     Total percentage holding of issued class following this notification*:
9.74%

14.     Any additional information

15.     Name of contact and telephone number for queries: NEIL BURDETT, 020 8457
8229

16.     Name and signature of duly authorised officer of the listed company
responsible for making this notification: NEIL BURDETT

17.     Date of notification: 10 NOVEMBER 2006

* any treasury shares held by the listed company should not be taken into
  account when calculating percentage


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