Canc of AIM trading facility

Synexus Clinical Research PLC
06 December 2007


For immediate release

6 December 2007

Synexus Clinical Research PLC (the "Company")

Board changes and cancellation of AIM trading facility

Further to the announcement earlier today by Sigma Acquisitions Ltd that its
offer to acquire all of the Company's share capital, in issue or to be issued,
is now unconditional in all respects, the Company has accepted the resignations
from the board of Malcolm Hughes and Ian Miscampbell with immediate effect.

The Company has also made application to the London Stock Exchange to cancel its
trading facility on AIM with effect from 8.00am on 14 December 2007.

For further enquiries:

Paul McCluskey - Finance Director (01257 230723)

Richard Evans - Brewin Dolphin Ltd, Nominated Adviser (0845 270 8600)

ENDS


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