Holding(s) in Company

System C Healthcare plc
08 November 2007



TR-1:    NOTIFICATION OF MAJOR INTERESTS IN SHARES

1. Identity of the issuer or the underlying issuer of existing shares to          
which voting rights are attached:

System C Healthcare PLC

2. Reason for the notification     (please tick the appropriate box or boxes)

An acquisition or disposal of voting rights                                 X

An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached

An event changing the breakdown of voting rights

Other (please specify):


3. Full name of person(s) subject to the notification obligation:        

Artemis Investment Management Ltd

4. Full name of shareholder(s) (if different from 3.):                            

Artemis New Enterprises

5. Date of the transaction (and date on which the threshold is crossed               
or reached if different):

6th November 2007

6. Date on which issuer notified:              

7th November 2007

7. Threshold(s) that is/are crossed or reached:    

5%

8. Notified details:


A: Voting rights attached to shares
Class/type of       Situation previous to the    Resulting situation after the triggering transaction
shares              Triggering transaction
                    Number of       Number of    Number of     Number of voting rights   % of voting rights
 if possible using  Shares          Voting       shares
the ISIN CODE                       Rights                     Direct       Indirect     Direct    Indirect

GB00B0940H91        3,675,000       3,675,000    4,725,000     4,725,000                 5.28%


B: Financial Instruments
Resulting situation after the triggering transaction
Type of financial    Expiration date Exercise/ Conversion      Number of voting rights    % of voting
instrument                           Period/ Date              that may be acquired if    rights
                                                               the instrument is
                                                               exercised/ converted.


Total (A+B)
Number of voting rights                            % of voting rights

4,725,000                                          5.28%


9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable:


Proxy Voting:

10. Name of the proxy holder:

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting rights:


13. Additional information:

14. Contact name:                             Jane Conner

15. Contact telephone number:                 01622 691616




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