Directors' Dealings / issue o

RNS Number : 8239V

Fulcrum Pharma PLC

16 July 2009

FULCRUM PHARMA PLC

('the Company')

Directors' Dealings and Issue of Options

The Company was informed on 16 July 2009 that on 16 July 2009 certain Directors of the Company bought ordinary shares of 1 penny each in the Company, as detailed below at a price of 3.2705 pence per share.

	Shares purchased	Shareholding after acquisition	Percentage of Issued Share Capital
Grahame Cook (Non-executive Chairman)	1,000,000	1,600,000	0.90%
Frank Armstrong (CEO)	250,000	850,000	0.48%
Barry Knight (CFO)	100,000	100,000	0.06%

The Company also announces that on 13 July 2009 the following options were issued to Barry Knight, CFO of the Company.

	No of options	Option price (pence)	Exercise Period
Barry Knight (CFO)	800,000	2.125	10 years
Barry Knight (CFO)	2,300,000	6	10 years
Barry Knight (CFO)	2,300,000	12	10 years