Holding(s) in Company

Fulcrum Pharma PLC
30 May 2002


             Fulcrum Pharma plc ('Fulcrum Pharma' or 'the Company')

                               Holding in Company


The Company has today been informed that World Life Sciences plc has, since 15
January 2002, sold in aggregate 2,425,000 ordinary shares in Fulcrum Pharma and
now holds 3,660,000 ordinary shares representing 5.95% of the Company's issued
share capital.


                      This information is provided by RNS
            The company news service from the London Stock Exchange