Opening of new US office

Fulcrum Pharma PLC
06 November 2007



                               FULCRUM PHARMA PLC
                         ('the Group' or 'the Company')


     Official Opening of Ann Arbor Office to Serve Growing US Customer Base

Fulcrum Pharma plc (AIM: FUL), the drug development and strategic outsourcing
services company, is pleased to announce that it has opened an office in Ann
Arbor, Michigan as part of the Group's planned expansion.

The Ann Arbor office, which is located at 900 Victors Way, Suite 160, Ann Arbor,
MI 48108, will complement Fulcrum's other US office in Research Triangle Park,
North Carolina, and will allow the Group to further develop the depth of the
Group's resources in drug development, project management and regulatory
affairs. Fulcrum operates six other offices throughout the EU and Japan.

Staff recruitment has already begun at the Ann Arbor office and Fulcrum is
benefiting from the pool of experienced talent in the region enabling it to
recruit drug development staff with considerable experience. The Ann Arbor
office will focus on early drug development services, with emphasis on
preclinical development.

The opening of the Ann Arbor office represents another significant milestone in
the Group's planned expansion, which is seeing Fulcrum increase both the range
of its services and the volume of work it is able to carry out for its
international client base.

Jon Court, Chief Executive of Fulcrum Pharma, said:

'The opening of the Ann Arbor office is another demonstration of our commitment
to the US Market and our provision of drug development services to the
biotechnology and pharmaceutical industries. It will enable us to provide an
even more efficient service to our customers.'

FOR FURTHER INFORMATION, PLEASE CONTACT:

Fulcrum Pharma PLC
Jon Court, Chief Executive           Tel: [phone]

Seymour Pierce
Jonathan Wright                      Tel: [phone]


About Fulcrum Pharma plc

Fulcrum Pharma plc is a drug development and regulatory services business that
provides global expertise to achieve drug development and regulatory approval
milestones.

Fulcrum Pharma offers immediate access to a highly credible, integrated
development team that provides strategic and operational leadership required to
ensure that new drugs move smoothly from discovery research to product approval

Fulcrum Pharma is listed on the AIM Market of the London Stock Exchange

The following can be used for a trade press announcement

About Fulcrum Pharma plc

Fulcrum Pharma plc is a drug development and regulatory services business that
provides global expertise to achieve drug development and regulatory approval
milestones.

Fulcrum Pharma offers immediate access to a highly credible, integrated
development team that provides strategic and operational leadership required to
ensure that new drugs move smoothly from discovery research to product approval

Fulcrum Pharma is listed on the AIM Market of the London Stock Exchange





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