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Edison Investment Research Lim (SAR)

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Wednesday 05 May, 2021

Edison Investment Research Lim

Sareum Holdings (SAR): Treading the TYK2 trail

Edison Investment Research Limited
Sareum Holdings (SAR): Treading the TYK2 trail

05-May-2021 / 07:00 GMT/BST


London, UK, 5 May 2021


Sareum Holdings (SAR): Treading the TYK2 trail

Kinase inhibitor specialist Sareum develops small molecule therapeutics with application in oncology and autoimmune disease areas. Lead asset SDC-1801 targets the autoimmune space and is nearing an inflection point, with a planned clinical trial application (CTA) filing in mid-2021 and clinical progression in Q421. The other candidate, SDC-1802, is focused on cancer and holds first-in-class promise with value to be unlocked with clinical validation. The out-licensed assets, SRA737 and FLT3+Aurora kinase, are currently de-prioritised but offer upside potential on revived activity.


Despite stringent resource management, Sareum's liquidity position remains constricted (cash runway lasting till Q421 at current run-rate) with valuation potential contingent on timely raising of funds to take SDC-1801 to the clinic.

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1192519 05-May-2021 


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