Oxford Glycosciences

Holding(s) in Company

Oxford Glycosciences PLC
25 March 2003


NOTIFICATION OF MAJOR INTERESTS IN SHARES

Oxford GlycoSciences Plc

On 25 March 2003 the Company was informed that on 21 March 2003 Amvescap Plc
sold 5,892,971 shares (representing 10.52% of the Company's issued share
capital), bringing its total holding to 5,675,812  shares (representing 10.14%
of the Company's issued share capital). The registered holders are set out
below:

Vidacos Nominees Limited                     4,980,812

Chase Nominees Limited                       545,000

Mellon Bank Nominees Pittsburgh              150,000

The Company was further advised that the above holding includes the following
notifiable holdings: INVESCO Perpetual UK Growth Fund holds 3,065,987 shares
(5.47%), and INVESCO Perpetual International Equity Fund holds 1,914,825 shares
(3.4%) both registered in the name of Vidacos Nominees Limited.  INVESCO
Perpetual Income Fund no longer has a notifiable interest in the Company's
issued share capital

Name of contact and telephone number for queries

Pam Rixon 01235 208022

Name of authorised company official responsible for making this notification

John Ilett - Company Secretary

Date of notification 25 March 2003


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