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GlaxoSmithKline PLC (GSK)

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Friday 12 January, 2007

GlaxoSmithKline PLC

Director/PDMR Shareholding

GlaxoSmithKline PLC
12 January 2007


         Notification of Transactions of Directors, Persons Discharging
                 Managerial Responsibility or Connected Persons


The Administrators of the GlaxoSmithKline Performance Share Plan notified the
Company and the under-mentioned persons on 12 January 2007 of an increase in
their notional interests in Ordinary Shares at a price of £13.92 per share and
Ordinary Share ADRs at a price of $52.98 per ADR following the notional
re-investment of the dividend paid to shareholders on 4 January 2007.


                                         Ordinary Shares                    ADRs
Dr JP Garnier                                                           5,559.21
Mr J S Heslop                                   1,016.15
Dr M M Slaoui                                     340.26
Mrs C Bruck Slaoui                                 29.63
Mr R Bondy                                      2,104.41
Dr F Calhoun                                                              673.34
Mr J Clarke                                       916.09
Mr M Dunoyer                                      599.39
Dr R Greig                                                                440.17
Mr D Learmouth                                     99.49
Mr D Phelan                                                             1,036.94
Dr D Pulman                                       473.37                  440.17
Mr D Stout                                                              2,131.09
Mr C Viehbacher                                                         1,036.94
Mr A P Witty                                    1,933.99


The notional dividends accrued will be paid out in proportion to the percentage
of participants' Performance Share Plan holdings that vest following the end of
the relevant three year measurement period.

This notification relates to a transaction notified in accordance with
Disclosure Rules 3.1.4R(1)(a) and 3.1.4R(1)(b).


S M Bicknell
Company Secretary

12 January 2007


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