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Oxford Asymmetry (OAI)


Friday 22 September, 2000

Oxford Asymmetry

Offer Update - Replacement

Oxford Asymmetry International PLC
22 September 2000

The issuer has advised that the announcement released under RNS No 3663R today
at 07:30 should appear under the Company Name Oxford Asymmetry International PLC
and Not Evotec BioSystems AG as originally shown.  The headline should read
'Offer Update' and not as originally shown.

All other details remain unchanged.

Not for release, publication or distribution in or into the United States,
Australia, Canada or Japan.

                     Result of EVOTEC Shareholder meeting

The Board of EVOTEC announces that at the general meeting of EVOTEC
Shareholders held on 21 September 2000, the following resolutions necessary to
implement the offer were duly passed:

(i)  to effect the increase of the share capital of EVOTEC for the purposes 
of implementing the Offer; and

(ii) to approve and implement the Offer and acquisition of OAI Shares by

At the meeting, Michael Redmond, Director of OAI, was elected to the
Supervisory Board of EVOTEC with immediate effect.


Lehman Brothers                                  Tel:  +44 (0)20 7601 0011
Warwick Ball

Definitions  used  in  the offer document dated 12 August 2000 have the same
meanings when used in this announcement, unless the context requires

Lehman  Brothers, which is regulated in the UK by The Securities and Futures
Authority Limited, is acting for EVOTEC BioSystems AG in connection with the
Offer and no-one else and will not be responsible to anyone other than EVOTEC
BioSystems AG for providing the protections afforded to customers of Lehman
Brothers, nor for providing advice in relation to the Offer.

The Offer is not being made, directly or indirectly, in or into Australia,
Canada or Japan, and it may not be accepted in or from Australia, Canada or
Japan.  In addition, the Offer is not being made, directly or indirectly in or
into the United States, and, subject to certain exceptions, the Offer may not
be accepted from the United States.

The New EVOTEC Shares proposed to be issued in connection with the Offer will
not be registered under the U.S. Securities Act of 1933, as amended.  This
announcement does not constitute an offer of securities for sale in the United
States.  No public offering of securities will be made in the United States in
connection with the Offer.


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